I had a typo in my original post - the low impedence setting on my Grace Design Alix Preamp (feeding an AER Compact 60 Slope) is actually 330KΩ - sorry for any confusion. I'd submitted my question to Taylor as well and here is their reply: "The ES2 is pretty flexible and can plug into any line input >10kΩ without issue. On your amp, I'd try both the medium and high settings to see which one sounded better." I tried all three impedence settings - as suspected there wasn't a huge difference but there was some slight difference. I favored the 330KΩ setting, so that's where it will remain. How to describe the difference - very subtle but in the higher settings the bass notes seemed to sound ever so slightly overloaded. YMMV. Thanks for all the feedback (pun intended). Chris.