On my M522, I first swapped for a Taylor bone saddle. Sadly. It was not tall enough... and no, I hadn't sanded it down but I did have to thin it a tad). I didn't notice any difference in tone quality. Admittedly, I've only had it a couple of months but it certainly didn't get worse. Next, I had Bob Colosi fashion one from West African ivory and it seems a bit brighter and perhaps louder now. But it's very subtle at best. I'll have to pop the Tusq saddle back in and see. It'll have to wait for the next string change though. I loved it before and that hasn't changed in the least
JV