The problem with bone, from what I understand, is that it can be inconsistent from one nut/saddle to another. Some people have swapped out their Tusq for bone and really liked the difference; others have swapped out only to put the Tusq back on. Nut/saddle material is like strings and picks: if you're looking for a different sound you just have to experiment yourself and see what happens. There are so many different views between guitar players, and none of us can say what would be best for you. What I may think is a great sound, you may think "Ugh!"
